PARP14
Sign in to saveAlso known as ARTD8, BAL2, PARP-14, pART8, poly(ADP-ribose) polymerase family member 14
protein-coding gene in the species Homo sapiens
Gene data
PARP14- Name
- poly(ADP-ribose) polymerase family member 14
- Type
- protein-coding
- Position
- 122,680,212–122,730,840 (+)
- Aliases
- ARTD8, BAL2, PARP-14, pART8
- Ensembl
- ENSG00000173193
- RefSeq RNA
- NM_017554.3, XM_011512929.3, XM_054346948.1, XR_007095695.1, XR_008486737.1
- RefSeq protein
- NP_060024.2, XP_011511231.1, XP_054202923.1
This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
negative regulation of gene expressionnegative regulation of gene expressionNAD+ catabolic processpositive regulation of tyrosine phosphorylation of STAT proteinnegative regulation of tyrosine phosphorylation of STAT proteinnegative regulation of DNA-templated transcriptionnegative regulation of type II interferon-mediated signaling pathwaynegative regulation of type II interferon-mediated signaling pathway
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
poly(ADP-ribose) polymerase family member 14
- Symbol
- PARP14
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:122,680,212-122,730,840
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI