Structure via PubChem · Public domain (PubChem)
penciclovir
Sign in to saveAlso known as VTA123, PCV, 9-(4-hydroxy-3-hydroxymethylbut-1-yl)-guanine, PE2, 9-[2-hydroxy-1-(hydroxymethyl)-ethoxymethyl]guanine, 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine, 9-(4-hydroxy-3-(hydroxymethyl)butyl)guanine, BRL-39123
Penciclovir is a guanosine analogue antiviral medication used for the treatment of various herpesvirus infections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. It is used as a topical treatment. It is sold under the brand name Denavir among others.
Chemical data
- Formula
- C10H15N5O3
- Molecular weight
- 253.26 g/mol
- IUPAC name
- 2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1H-purin-6-one
- SMILES
- C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
- InChIKey
- JNTOCHDNEULJHD-UHFFFAOYSA-N
- XLogP
- -1.9
- Polar surface area
- 126 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 253.117
Show 3 more facts
- chemical formula
- C₁₀H₁₅N₅O₃
- canonical SMILES
- C1=NC2=C(N1CCC(CO)CO)NC(=NC2=O)N
- World Health Organisation international non-proprietary name
- penciclovir
via Wikidata · CC0
~2 min read
Article
3 sectionsContents
- Medical use
- Mechanism of action
- References
Penciclovir is a guanosine analogue antiviral medication used for the treatment of various herpesvirus infections. It is a nucleoside analogue which exhibits low toxicity and good selectivity. It is used as a topical treatment. It is sold under the brand name Denavir among others.
Penciclovir was approved for medical use in 1996.