pericine
Sign in to savePericine is one of a number of indole alkaloids found in the tree Picralima nitida, commonly known as akuamma. As with some other alkaloids from this plant such as akuammine, pericine has been shown to bind to mu opioid receptors in vitro, and has an IC50 of 0.6 μmol, within the range of a weak analgesic. It may also have convulsant effects.
Wikidata facts
- Mass
- 278.178
Show 3 more facts
- chemical formula
- C₁₉H₂₂N₂
- canonical SMILES
- CC=C1CN2CCC1C(=C)C3=C(CC2)C4=CC=CC=C4N3
- isomeric SMILES
- C/C=C\1/CN2CC[C@H]1C(=C)C3=C(CC2)C4=CC=CC=C4N3
Sources (2)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- See also
- References
Pericine is one of a number of indole alkaloids found in the tree Picralima nitida, commonly known as akuamma. As with some other alkaloids from this plant such as akuammine, pericine has been shown to bind to mu opioid receptors in vitro, and has an IC50 of 0.6 μmol, within the range of a weak analgesic. It may also have convulsant effects.
Pericine has been prepared in the laboratory by total synthesis.