filodulcina

Chemical data

Formula

C16H14O5

Molecular weight

286.28 g/mol

IUPAC name

(3R)-8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-3,4-dihydroisochromen-1-one

SMILES

COC1=C(C=C(C=C1)[C@H]2CC3=C(C(=CC=C3)O)C(=O)O2)O

InChIKey

PBILBHLAPJTJOT-CQSZACIVSA-N

XLogP

3.1

Polar surface area

76 Ų

H-bond donors

2

H-bond acceptors

5

Formal charge

0

via PubChem

Drug data · ChEMBL

Molecule type

Small molecule

via ChEMBL · EBI

• Phyllodulcin improves hippocampal long-term potentiation in 5XFAD mice.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
• Phyllodulcin from the hexane fraction of Hydrangea macrophylla inhibits glucose-induced lipid accumulation and reactive oxygen species generation in Caenorhabditis elegans.Bioscience, biotechnology, and biochemistry · 2024
• Phyllodulcin, a Natural Sweetener, Regulates Obesity-Related Metabolic Changes and Fat Browning-Related Genes of Subcutaneous White Adipose Tissue in High-Fat Diet-Induced Obese Mice.Nutrients · 2017
• Metabolic fate of orally administered phyllodulcin in rats.Journal of natural products · 2004
• Relative sweetness and sweetness quality of phyllodulcin [(3R)-8-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-1H-isochromen-1-one].Food science and biotechnology · 2016

via PubMed

Wikidata facts

Mass

286.084124

Has use

sweetener

via Wikidata · CC0