Also known as polyketides
In organic chemistry, polyketides are a class of natural products derived from a precursor molecule consisting of a chain of alternating ketone (, or its reduced forms) and methylene () groups: . First studied in the early 20th century, discovery, biosynthesis, and application of polyketides has evolved. It is a large and diverse group of secondary metabolites caused by its complex biosynthesis which resembles that of fatty acid synthesis. Because of this diversity, polyketides can have various medicinal, agricultural, and industrial applications. Many polyketides are medicinal or exhibit acut
Research
113,120 papers- Polyketide Cyclizations for the Synthesis of Polyaromatics.Angewandte Chemie (International ed. in English) · 2020
- Structure and Mechanisms of Assembly-Line Polyketide Synthases.Annual review of biochemistry · 2024
- Module-Based Polyketide Synthase Engineering for de Novo Polyketide Biosynthesis.ACS synthetic biology · 2023
- Complexity of fungal polyketide biosynthesis and function.Molecular microbiology · 2024
- Cis double bond formation in polyketide biosynthesis.Natural product reports · 2021
via PubMed
Wikidata facts
- Subclass of
- biomolecule
- Said to be same as
- acetogenins
Show 2 more facts
- Commons category
- Polyketides
- topic's main category
- Category:Polyketides
Sources (2)
via Wikidata · CC0
Article · 中文
聚酮(英語:Polyketides)是一類由細菌、真菌、植物與動物所生產出來的次级代谢产物,這類物質對生物的發育生長而言非必要,但可用於防衛或細胞間的溝通。 聚酮是源自乙醯基(acetyl)與(propionyl)的聚合。可能的作用有抗生素、、細胞穩定(cytostatic)或天然殺蟲劑等。具有商業價值。
Abstract from DBpedia / Wikipedia · CC BY-SA