{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! | Epothilones |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones A (R = H) and B (R = Me) Epothilones A (R = H) and B (R = CH3) |- | Chemical formulae | A: C26H39NO6S B: C27H41NO6S |- | Molecular masses | A: 493.66 g/mol B: 507.68 g/mol |- | CAS numbers | A: 152044-53-6 B: 152044-54-7 |- | PubChem | A: 448799 B: 448013 |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones C (R = H) and D (R = Me) Epothilones C (R = H) and D (R = CH3) |- | Chemi
{| class="toccolours" border="1" style="float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;" ! | Epothilones |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones A (R = H) and B (R = Me) Epothilones A (R = H) and B (R = CH3) |- | Chemical formulae | A: C26H39NO6S B: C27H41NO6S |- | Molecular masses | A: 493.66 g/mol B: 507.68 g/mol |- | CAS numbers | A: 152044-53-6 B: 152044-54-7 |- | PubChem | A: 448799 B: 448013 |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones C (R = H) and D (R = Me) Epothilones C (R = H) and D (R = CH3) |- | Chemical formulae | C: C26H39NO5S D: C27H41NO5S |- | Molecular masses | C: 477.66 g/mol D: 491.68 g/mol |- | CAS numbers | C: 186692-73-9 D: 189453-10-9 |- | PubChem | C: 9891226 D: 447865 |- | align="center" colspan="2" bgcolor="#ffffff"| 250px|Epothilones E (R = H) and F (R = Me) Epothilones E (R = H) and F (R = CH3) |- | Chemical formulae | E: C26H39NO7S F: C27H41NO7S |- | Molecular masses | E: 509.66 g/mol F: 523.68 g/mol |- | CAS numbers | E: 201049-37-8 F: 208518-52-9 |- | PubChem | E: 9806341 F: 9914741 |- | | Disclaimer and references |}
Epothilones are a class of potential cancer drugs. Like taxanes, they prevent cancer cells from dividing by interfering with tubulin, but in early trials, epothilones have better efficacy and milder adverse effects than taxanes.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).