Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C7H9N2O+
- Molecular weight
- 137.16 g/mol
- IUPAC name
- (NZ)-N-[(1-methylpyridin-1-ium-2-yl)methylidene]hydroxylamine
- SMILES
- C[N+]1=CC=CC=C1/C=N\O
- InChIKey
- JBKPUQTUERUYQE-UHFFFAOYSA-O
- XLogP
- 1
- Polar surface area
- 36.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 1
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1964
- Admin. routes
- oral, parenteral
- Indications
- poisoning, organophosphate poisoning
via ChEMBL · EBI
Research
1,679 papers- Pralidoxime.Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology · 2016
- Pralidoxime safety and toxicity in children.Prehospital emergency care · 2007
- Pralidoxime and pesticide poisoning: A question of severity?Biomedical journal · 2016
- Pralidoxime improves the hemodynamics and survival of rats with peritonitis-induced sepsis.PloS one · 2021
- Pralidoxime-like reactivator with increased lipophilicity - Molecular modeling and in vitro study.Chemico-biological interactions · 2023
via PubMed
Wikidata facts
- Mass
- 137.071488
- Has use
- medication
Show 8 more facts
- route of administration
- subcutaneous injection
- isomeric SMILES
- C[N+]1=CC=CC=C1/C=N/O
- canonical SMILES
- CN1C=CC=CC1=C[NH+]=O
- World Health Organisation international non-proprietary name
- pralidoxime
- subject has role
- antidote
- physically interacts with
- acetylcholinesterase
- Commons category
- Pralidoxime
- chemical formula
- C₇H₉N₂O⁺
via Wikidata · CC0
Article · Deutsch
Pralidoxim (kurz 2-PAM) ist ein Antidot, das bei Vergiftung mit Organophosphaten angewendet werden kann und in verschiedenen chemischen Abwandlungen vorkommt. Eigentlich bezeichnet der Name Pralidoxim lediglich das zugrundeliegende Pyridiniumkation. Prominente Gegenionen sind Chlorid, Iodid und . Eine bessere Wirkung weist jedoch Trimedoxim auf.
Abstract from DBpedia / Wikipedia · CC BY-SA