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preeclampsia

Also known as Pre-eclampsia, preeclampsia, Pre-eclampsia or eclampsia superimposed on pre-existing hypertension, pregnancy associated hypertension, preeclampsia/eclampsia, toxaemia of pregnancy, hypertension induced by pregnancy, gestational hypertension, proteinuric hypertension of pregnancy

sindrome caratterizzata dalla presenza, singola o in associazione, di segni clinici quali edema, proteinuria o ipertensione in una donna gravida

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Key facts

Medical condition.name: Pre-eclampsia
Medical condition.image: Hypertrophic decidual vasculopathy high mag.jpg
Medical condition.caption: A micrograph showing hypertrophic decidual vasculopathy, a finding seen in gestational hypertension and pre-eclampsia. H&E stain.
Medical condition.field: Obstetrics
Medical condition.synonyms: Preeclampsia toxaemia (PET)
Medical condition.symptoms: High blood pressure, protein in the urine
Medical condition.complications: Red blood cell breakdown, low blood platelet count, impaired liver function, kidney problems, swelling, shortness of breath due to fluid in the lungs, eclampsia
Medical condition.onset: After 20 weeks of pregnancy
Medical condition.risks: Obesity, prior hypertension, older age, diabetes mellitus
Medical condition.diagnosis: BP > 140 mmHg systolic or 90 mmHg diastolic at two separate times
Medical condition.prevention: Aspirin, calcium supplementation, treatment of prior hypertension
Medical condition.treatment: Delivery, medications
Medical condition.medication: Labetalol, methyldopa, magnesium sulfate
Medical condition.frequency: 2–8% of pregnancies
Medical condition.deaths: 46,900 hypertensive disorders in pregnancy (2015)
Diagnostic.Name: Pre-eclampsia laboratory values
Diagnostic.Image: Preeclampsia Fishbone Schematic.PNG
Diagnostic.Alt: LDH/Uric Acid/AST/ALT/Plt/Cr

via Wikipedia infobox

Research

46,087 papers

Pre-eclampsia: pathogenesis, novel diagnostics and therapies.ReviewNature reviews. Nephrology · 2019Phipps EA, Thadhani R, Benzing T et al.DOI: 10.1038/s41581-019-0119-6
Pre-eclampsia: does cardiac function differ in HIV-positive and -negative women?ReviewCardiovascular journal of Africa · 2024Bhorat R, Bhorat I, Khaliq OP et al.DOI: 10.5830/CVJA-2023-005
Pre-eclampsia.ReviewLancet (London, England) · 2005Sibai B, Dekker G, Kupferminc MDOI: 10.1016/S0140-6736(05)17987-2
Midwives' knowledge of pre-eclampsia management: A scoping review.Women and birth : journal of the Australian College of Midwives · 2021Garti I, Gray M, Tan JY et al.DOI: 10.1016/j.wombi.2020.08.010
Pre-eclampsia: pathophysiology, diagnosis, and management.ReviewVascular health and risk management · 2011Uzan J, Carbonnel M, Piconne O et al.DOI: 10.2147/VHRM.S20181
Pre-eclampsia--still a disease of theories?ReviewCurrent opinion in obstetrics & gynecology · 1998Higgins JR, Brennecke SPDOI: 10.1097/00001703-199804000-00009
Pre-eclampsia: physiology and immunological aspects.ReviewEuropean journal of obstetrics, gynecology, and reproductive biology · 1995Vinatier D, Monnier JCDOI: 10.1016/0301-2115(95)02106-h
Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.ReviewBest practice & research. Clinical obstetrics & gynaecology · 2011Hutcheon JA, Lisonkova S, Joseph KSDOI: 10.1016/j.bpobgyn.2011.01.006

via PubMed

Article · Italiano

La preeclampsia, nota anche come gestosi (termine ormai in disuso), è una sindrome caratterizzata dalla presenza, singola o in associazione, di segni clinici quali edema, proteinuria o ipertensione in una donna gravida. Dalle iniziali delle parole inglesi di questi tre sintomi (Edema, Proteinuria, Hypertension) è stata coniata la sigla EPH, con la quale si indicava la concomitante presenza di questa triade sintomatologica (gestosi trisintomatica). Venivano inoltre adoperate le sigle EH per indicare la presenza di edema e ipertensione (gestosi bisintomatica di tipo EH) e PH per indicare la presenza di proteinuria e ipertensione (gestosi bisintomatica di tipo PH). Infine si potevano contemplare le cosiddette gestosi monosintomatiche di tipo E, P, e H a seconda del sintomo riscontrato. Poiché numerosissime casistiche raccolte nel corso degli anni dimostrarono l'aspecificità degli edemi (appannaggio di numerosissime gravidanze fisiologiche e perfino assenti in alcune forme severe di gestosi), si è deciso di modificare la denominazione della sindrome e di darne una definizione ed una classificazione più aderente alla realtà clinica, comprendendola nel più grande ambito dei fenomeni ipertensivi che possono interessare la paziente gravida.

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