โรคพิษแห่งครรภ์ระยะก่อนชัก

Key facts

Medical condition.name

Pre-eclampsia

Medical condition.image

Hypertrophic decidual vasculopathy high mag.jpg

Medical condition.caption

A micrograph showing hypertrophic decidual vasculopathy, a finding seen in gestational hypertension and pre-eclampsia. H&E stain.

Medical condition.field

Obstetrics

Medical condition.synonyms

Preeclampsia toxaemia (PET)

Medical condition.symptoms

High blood pressure, protein in the urine

Medical condition.complications

Red blood cell breakdown, low blood platelet count, impaired liver function, kidney problems, swelling, shortness of breath due to fluid in the lungs, eclampsia

Medical condition.onset

After 20 weeks of pregnancy

Medical condition.risks

Obesity, prior hypertension, older age, diabetes mellitus

Medical condition.diagnosis

BP > 140 mmHg systolic or 90 mmHg diastolic at two separate times

Medical condition.prevention

Aspirin, calcium supplementation, treatment of prior hypertension

Medical condition.treatment

Delivery, medications

Medical condition.medication

Labetalol, methyldopa, magnesium sulfate

Medical condition.frequency

2–8% of pregnancies

Medical condition.deaths

46,900 hypertensive disorders in pregnancy (2015)

Diagnostic.Name

Pre-eclampsia laboratory values

Diagnostic.Image

Preeclampsia Fishbone Schematic.PNG

Diagnostic.Alt

LDH/Uric Acid/AST/ALT/Plt/Cr

via Wikipedia infobox

• Pre-eclampsia: pathogenesis, novel diagnostics and therapies.ReviewNature reviews. Nephrology · 2019Phipps EA, Thadhani R, Benzing T et al.DOI: 10.1038/s41581-019-0119-6
• Pre-eclampsia: does cardiac function differ in HIV-positive and -negative women?ReviewCardiovascular journal of Africa · 2024Bhorat R, Bhorat I, Khaliq OP et al.DOI: 10.5830/CVJA-2023-005
• Pre-eclampsia.ReviewLancet (London, England) · 2005Sibai B, Dekker G, Kupferminc MDOI: 10.1016/S0140-6736(05)17987-2
• Midwives' knowledge of pre-eclampsia management: A scoping review.Women and birth : journal of the Australian College of Midwives · 2021Garti I, Gray M, Tan JY et al.DOI: 10.1016/j.wombi.2020.08.010
• Pre-eclampsia: pathophysiology, diagnosis, and management.ReviewVascular health and risk management · 2011Uzan J, Carbonnel M, Piconne O et al.DOI: 10.2147/VHRM.S20181
• Pre-eclampsia--still a disease of theories?ReviewCurrent opinion in obstetrics & gynecology · 1998Higgins JR, Brennecke SPDOI: 10.1097/00001703-199804000-00009
• Pre-eclampsia: physiology and immunological aspects.ReviewEuropean journal of obstetrics, gynecology, and reproductive biology · 1995Vinatier D, Monnier JCDOI: 10.1016/0301-2115(95)02106-h
• Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy.ReviewBest practice & research. Clinical obstetrics & gynaecology · 2011Hutcheon JA, Lisonkova S, Joseph KSDOI: 10.1016/j.bpobgyn.2011.01.006

via PubMed