Structure via PubChem · Public domain (PubChem)
acedapsone
Sign in to saveAcedapsone (INN) is an antimicrobial drug, which also has antimalarial activity.
Chemical data
- Formula
- C16H16N2O4S
- Molecular weight
- 332.4 g/mol
- IUPAC name
- N-[4-(4-acetamidophenyl)sulfonylphenyl]acetamide
- SMILES
- CC(=O)NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)NC(=O)C
- InChIKey
- AMTPYFGPPVFBBI-UHFFFAOYSA-N
- XLogP
- 1.1
- Polar surface area
- 101 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
52 papers- Death Anxiety and Correlates in Cancer Patients Receiving Palliative Care.Journal of palliative medicine · 2023
- Metabolism and interactions of antileprosy drugs.Biochemical pharmacology · 2020
- Acedapsone treatment of leprosy patients: response versus drug disposition.The American journal of tropical medicine and hygiene · 1977
- Acedapsone (DADDS) treatment of leprosy patients in the Karimui of Papua New Guinea: status at six years.The American journal of tropical medicine and hygiene · 1975
- The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use.Parasites & vectors · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 332.083
Show 4 more facts
- canonical SMILES
- CC(=O)NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)NC(=O)C
- subject has role
- antimalarial
- chemical formula
- C₁₆H₁₆N₂O₄S
- Commons category
- Acedapsone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Acedapsone (INN) is an antimicrobial drug, which also has antimalarial activity.
Acedapsone is the INN for diacetyldapsone. It was synthesized and developed in 1937 by Ernest Fourneau and his team in the pharmaceutical chemistry laboratory of Pasteur Institute, and it was marketed as Rodilone by the Rhône-Poulenc company.
Excerpted from Wikipedia’s “acedapsone” article, available under the CC BY-SA 4.0 licence.