progestogen
Sign in to saveProgestogens, also sometimes written progestins, progestagens or gestagens, are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). Progesterone is the major and most important progestogen in the body. The progestogens are named for their function in maintaining pregnancy (i.e., progestational), although they are also present at other phases of the estrous and menstrual cycles.
Key facts
- Drug class.Image
- File:Progesterone.svg
- Drug class.ImageClass
- skin-invert-image
- Drug class.Caption
- Progesterone, the major progestogen in humans and a widely used medication.
- Drug class.Width
- 225px
- Drug class.Synonyms
- Progestins; Progestagens; Gestagens,
- Drug class.Use
- Contraception, menopause, hypogonadism, transgender women, others
- Drug class.MeshID
- D011372
- Drug class.ATC_prefix
- G03D
- Drug class.Biological_target
- Progesterone receptors (PRA, PRB, PRC, mPRs (e.g., mPRα, mPRβ, mPRγ, mPRδ, others))
via Wikipedia infobox
Article
11 sectionsContents
- Types and examples
- Biological function
- Biochemistry
- Biosynthesis
- Ovarian production
- Placental production
- Chemistry
- Medical use
- References
- Further reading
- External links
Progestogens, also sometimes written progestins, progestagens or gestagens, are a class of natural or synthetic steroid hormones that bind to and activate the progesterone receptors (PR). Progesterone is the major and most important progestogen in the body. The progestogens are named for their function in maintaining pregnancy (i.e., progestational), although they are also present at other phases of the estrous and menstrual cycles.
The progestogens are one of three types of sex hormones, the others being estrogens like estradiol and androgens/anabolic steroids like testosterone. In addition, they are one of the five major classes of steroid hormones, the others being the androgens, estrogens, glucocorticoids, and mineralocorticoids, as well as the neurosteroids. All endogenous progestogens are characterized by their basic 21-carbon skeleton, called a pregnane skeleton (C21). In similar manner, the estrogens possess an estrane skeleton (C18), and androgens, an androstane skeleton (C19).