Prothionamide

Key facts

Drug.Verifiedfields

changed

Drug.Watchedfields

changed

Drug.verifiedrevid

447906208

Drug.IUPAC_name

2-propylpyridine-4-carbothioamide

Drug.image

Protionamide.svg

Drug.image_class

skin-invert-image

Drug.image2

Prothionamide 3D ball.png

Drug.image_class2

bg-transparent

Drug.ATC_prefix

J04

Drug.ATC_suffix

AD01

Drug.CAS_number

14222-60-7

Drug.PubChem

666418

Drug.DrugBank

DB12667

Drug.UNII

76YOO33643

Drug.ChemSpiderID

579891

Drug.C

9

Drug.H

12

Drug.N

2

via Wikipedia infobox

Chemical data

Formula

C9H12N2S

Molecular weight

180.27 g/mol

IUPAC name

2-propylpyridine-4-carbothioamide

SMILES

CCCC1=NC=CC(=C1)C(=S)N

InChIKey

VRDIULHPQTYCLN-UHFFFAOYSA-N

XLogP

1.5

Polar surface area

71 Ų

H-bond donors

1

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 3

Molecule type

Small molecule

Indications

tuberculosis, pulmonary tuberculosis

via ChEMBL · EBI

• Prothionamide.2006
• Prothionamide.Tuberculosis (Edinburgh, Scotland) · 2008
• Drug-induced hypothyroidism in tuberculosis.Expert review of endocrinology & metabolism · 2024
• [Clinical analysis of protionamide and para-aminosalicylic acid induced hepatotoxicity in 129 cases].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases · 2013
• Validation of a universal and highly sensitive two-dimensional liquid chromatography-tandem mass spectrometry methodology for the quantification of pyrazinamide, ethambutol, protionamide, and clofazimine in different biological matrices.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2020

via PubMed

Wikidata facts

Has part

carbon

Mass

180.072

via Wikidata · CC0