PTGDR2
Sign in to saveAlso known as CD294, CRTH2, DL1R, DP2, GPR44, prostaglandin D2 receptor 2
protein-coding gene in the species Homo sapiens
Gene data
PTGDR2- Name
- prostaglandin D2 receptor 2
- Type
- protein-coding
- Position
- 60,850,933–60,855,950 (−)
- Aliases
- CD294, CRTH2, DL1R, DP2, GPR44
- Ensembl
- ENSG00000183134
- RefSeq RNA
- NM_004778.3
- RefSeq protein
- NP_004769.2
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
prostaglandin D2 receptor 2
- Symbol
- PTGDR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:60,850,933-60,855,987
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 3508
- exact match
- identifiers.org/ncbigene/11251
- genomic end
- 60855950
- genomic start
- 60850933
- cytogenetic location
- 11q12.2
Sources (4)
via Wikidata · CC0
Connections
Q180686
Entity
eosinophil
Entity
basophil
Entity
G protein-coupled recepteishon
Entity
indomethacin
Entity
chemotaxis
Entity
T helper cell
Entity
ligand
Entity
diglyceride
Entity
cytotoxic T cell
Entity
prostacyclin
Entity
Ensembl genome database project
Entity
prostaglandin E2
Entity
CD1
Entity
prostaglandin F2α
Entity
clonixin
Entity
prostaglandin receptor
Entity
PTGER3
Gene
eicosanoid receptor
Entity
protein
Entity