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GeneQ18030910· pop 6· linked from 109 articles

Also known as BRK, protein tyrosine kinase 6

Tyrosine-protein kinase 6 is an enzyme that in humans is encoded by the PTK6 gene.

Gene data

PTK6
Name
protein tyrosine kinase 6
Type
protein-coding
Position
63,528,001–63,537,376 (−)
Aliases
BRK
RefSeq RNA
NM_001256358.2, NM_005975.4
RefSeq protein
NP_001243287.1, NP_005966.1

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].

via MyGene.info

Gene · Ensembl

protein tyrosine kinase 6

Symbol
PTK6
Biotype
Protein coding
Organism
Homo sapiens
Location
20:63,526,306-63,537,770
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein PTK6 PDB 1rja.png
Show 5 more facts
HomoloGene ID
68494
genomic end
63537376
genomic start
62159778
cytogenetic location
20q13.33
Sources (3)

via Wikidata · CC0

~1 min read

Article

5 sections
Contents
  • Function
  • Clinical significance
  • Interactions
  • References
  • Further reading

Tyrosine-protein kinase 6 is an enzyme that in humans is encoded by the PTK6 gene.

== Function ==

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