RARG

Also known as NR1B3, RARC, retinoic acid receptor gamma, RARgamma

protein-coding gene in the species Homo sapiens

Gene data

RARG

Name: retinoic acid receptor gamma
Type: protein-coding
Position: 53,210,566–53,232,980 (−)
Aliases: NR1B3, RARC, RARgamma
Ensembl: ENSG00000172819
RefSeq RNA: NM_000966.6, NM_001042728.3, NM_001243730.2, NM_001243731.2, NM_001243732.2
RefSeq protein: NP_000957.1, NP_001036193.1, NP_001230659.1, NP_001230660.1, NP_001230661.1

This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].