RFX3
Sign in to saveAlso known as regulatory factor X3
Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.
Gene data
RFX3- Name
- regulatory factor X3
- Type
- protein-coding
- Position
- 3,218,297–3,526,919 (−)
- Ensembl
- ENSG00000080298
- RefSeq RNA
- NM_001282116.2, NM_001282117.2, NM_001377999.1, NM_002919.4, NM_134428.3
- RefSeq protein
- NP_001269045.1, NP_001269046.1, NP_001364928.1, NP_002910.1, NP_602304.1
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
regulatory factor X3
- Symbol
- RFX3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:3,218,297-3,526,919
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7917
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5991
- genomic end
- 3526004
- genomic start
- 3218297
- chromosome
- human chromosome 9
- cytogenetic location
- 9p24.2
- expressed in
- entorhinal cortex
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
Excerpted from Wikipedia’s “RFX3” article, available under the CC BY-SA 4.0 licence.