Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene.
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
via MyGene.info
Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene.
== Function ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).