RGS14
Sign in to saveAlso known as regulator of G protein signaling 14
Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene.
Gene data
RGS14- Name
- regulator of G protein signaling 14
- Type
- protein-coding
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
regulator of G protein signaling 14
- Symbol
- RGS14
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:177,357,654-177,374,390
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Regulator of G-protein signaling 14 (RGS14) is a protein that in humans is encoded by the RGS14 gene.
== Function ==
Excerpted from Wikipedia’s “RGS14” article, available under the CC BY-SA 4.0 licence.
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