RGS17
Sign in to saveAlso known as RGS-17, RGSZ2, hRGS17, regulator of G-protein signaling 17, regulator of G protein signaling 17
Regulator of G-protein signaling 17 is a protein that in humans is encoded by the RGS17 gene.
Gene data
RGS17- Name
- regulator of G protein signaling 17
- Type
- protein-coding
- Position
- 153,004,449–153,131,306 (−)
- Aliases
- RGS-17, RGSZ2, hRGS17
- Ensembl
- ENSG00000091844
- RefSeq RNA
- NM_012419.5, XM_047418634.1, XM_047418635.1, XM_047418636.1, XM_054355154.1
- RefSeq protein
- NP_036551.3, XP_047274590.1, XP_047274591.1, XP_047274592.1, XP_054211129.1
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
regulator of G protein signaling 17
- Symbol
- RGS17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:153,004,449-153,131,306
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Regulator of G-protein signaling 17 is a protein that in humans is encoded by the RGS17 gene.
== Function ==
Excerpted from Wikipedia’s “RGS17” article, available under the CC BY-SA 4.0 licence.
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