RPS6KA5
Sign in to saveAlso known as MSK1, MSPK1, RLPK, ribosomal protein S6 kinase A5
Ribosomal protein S6 kinase alpha-5 is an enzyme that in humans is encoded by the RPS6KA5 gene. This kinase, together with RPS6KA4, are thought to mediate the phosphorylation of histone H3, linked to the expression of immediate early genes.
In the Vinony graph
Vinony's link graph records 303 inbound references to RPS6KA5, and connects out to Q180686, human chromosome 14 and Ensembl genome database project.
It is catalogued under topics including EC 2.7.11 and Genes on human chromosome 14.
Vinony links it to 4 Wikipedia language editions.
Gene data
RPS6KA5- Name
- ribosomal protein S6 kinase A5
- Type
- protein-coding
- Position
- 90,847,861–91,060,685 (−)
- Aliases
- MSK1, MSPK1, RLPK
- Ensembl
- ENSG00000100784
- RefSeq RNA
- NM_001322227.2, NM_001322228.2, NM_001322229.2, NM_001322230.2, NM_001322231.2
- RefSeq protein
- NP_001309156.1, NP_001309157.1, NP_001309158.1, NP_001309159.1, NP_001309160.1
Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including histone-serine phosphorylation; positive regulation of histone modification; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
ribosomal protein S6 kinase A5
- Symbol
- RPS6KA5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:90,847,861-91,060,685
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein RPS6KA5 PDB 1vzo.png
Show 6 more facts
- HomoloGene ID
- 48302
- exact match
- identifiers.org/ncbigene/9252
- genomic start
- 90847861
- genomic end
- 91060641
- cytogenetic location
- 14q32.11
- Commons category
- Ribosomal protein S6 kinase alpha-5
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Ribosomal protein S6 kinase alpha-5 is an enzyme that in humans is encoded by the RPS6KA5 gene. This kinase, together with RPS6KA4, are thought to mediate the phosphorylation of histone H3, linked to the expression of immediate early genes.
==Interactions== RPS6KA5 has been shown to interact with CREB1.
Excerpted from Wikipedia’s “RPS6KA5” article, available under the CC BY-SA 4.0 licence.