samandarin
Sign in to saveAlso known as (1R,2S,3S,6R,8S,10S,11S,14R,16S)-2,6-dimethyl-19-oxa-17-azapentacyclo[14.2.1.02,14.03,11.06,10]nonadecan-8-ol
Samandarin or Samandarine is the main steroidal alkaloid secreted by the fire salamander (Salamandra salamandra). The compound is extremely toxic (LD50 = 70 μg/kg in mice). Poisoning can cause convulsions, respiratory paralysis, and eventual death. Samandarin is also believed to be the active ingredient in Salamander brandy, a Slovenian traditional medicinal alcoholic drink with purported hallucinogenic and aphrodisiac effects.
~10 min read
Encyclopedic overview
10 sectionsContents
- Samandarine family
- History
- Discovery
- Use in Salamander Brandy
- Biological effects
- Synthesis
- By the salamander
- In the lab
- See also
- References
Samandarin or Samandarine is the main steroidal alkaloid secreted by the fire salamander (Salamandra salamandra). The compound is extremely toxic (LD50 = 70 μg/kg in mice). Poisoning can cause convulsions, respiratory paralysis, and eventual death. Samandarin is also believed to be the active ingredient in Salamander brandy, a Slovenian traditional medicinal alcoholic drink with purported hallucinogenic and aphrodisiac effects.
==Samandarine family== center|thumb|upright=1.5|Nine isolated compounds in the samandarine family. thumb|upright=1.0|right|Fire salamander (Salamandra salamandra).
Excerpted from Wikipedia’s “samandarin” article, available under the CC BY-SA 4.0 licence.