SCN3A
Sign in to saveAlso known as NAC3, Nav1.3, sodium voltage-gated channel alpha subunit 3, FFEVF4, EIEE62, DEE62
Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the SCN3A gene.
Gene data
SCN3A- Name
- sodium voltage-gated channel alpha subunit 3
- Type
- protein-coding
- Aliases
- DEE62, EIEE62, FFEVF4, NAC3, Nav1.3
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
sodium voltage-gated channel alpha subunit 3
- Symbol
- SCN3A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:165,087,516-165,204,093
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SCN3A PDB 1byy.png
Show 10 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 56005
- exact match
- identifiers.org/ncbigene/6328
- genomic end
- 165204050
- genomic start
- 165087526
- expressed in
- superior frontal gyrus
- chromosome
- human chromosome 2
- cytogenetic location
- 2q24.3
- genetic association
- focal epilepsy
- Commons category
- SCN3A
Sources (7)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the SCN3A gene.
== Function ==
Excerpted from Wikipedia’s “SCN3A” article, available under the CC BY-SA 4.0 licence.