مستقبل السيكريتين

Also known as SR, secretin receptor

جين في إنسان عاقل

Gene data

SCTR

Name: secretin receptor
Type: protein-coding
Position: 119,439,839–119,525,301 (−)
Aliases: SECR, SR
Ensembl: ENSG00000080293
RefSeq RNA: NM_002980.3, XM_011511621.3, XM_017004670.2, XM_047445399.1, XM_047445400.1
RefSeq protein: NP_002971.2, XP_011509923.1, XP_016860159.2, XP_047301355.1, XP_047301356.1

The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

diet induced thermogenesis cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway

Molecular function

transmembrane signaling receptor activity G protein-coupled receptor activity G protein-coupled peptide receptor activity secretin receptor activity secretin receptor activity secretin receptor activity peptide hormone binding

Cellular component

cytoplasmic microtubule plasma membrane plasma membrane plasma membrane plasma membrane membrane basolateral plasma membrane basolateral plasma membrane

Pathways

Neuroactive ligand-receptor interaction - Homo sapiens (human)Pancreatic secretion - Homo sapiens (human)Bile secretion - Homo sapiens (human)Signal Transduction Signaling by GPCR Class B/2 (Secretin family receptors)GPCR downstream signalling G alpha (s) signalling events Glucagon-type ligand receptors GPCR ligand binding

via MyGene.info

Gene · Ensembl

secretin receptor

Symbol: SCTR
Biotype: Protein coding
Organism: Homo sapiens
Location: 2:119,439,839-119,525,301
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 68290
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/6344
genomic end: 120282070
genomic start: 120197419
chromosome: human chromosome 2
cytogenetic location: 2q14.2
different from: Stream Control Transmission Protocol

Sources (3)

via Wikidata · CC0

Article · العربية

مستقبل السيكريتين البشري أو مستقبل السكريتين البشري أو مستقبل المفرزين البشري (بالإنجليزية: Human secretin receptor)‏ واسم الجين SCTR، هو مستقبل مقترن بالبروتين ج والذي يرتبط بالسيكريتين، ويُعتبر عضو رئيسي في فصيلة بي من المستقبلات المقترنة بالبروتين ج.

Abstract from DBpedia / Wikipedia · CC BY-SA

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