Structure via PubChem · Public domain (PubChem)
segesterone acetate
Sign in to saveAlso known as Nestorone, 16-methylene-17α-acetoxy-19-norprogesterone
chemical compound
Chemical data
- Formula
- C23H30O4
- Molecular weight
- 370.5 g/mol
- IUPAC name
- [(8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylidene-3-oxo-2,6,7,8,9,10,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
- SMILES
- CC(=O)[C@]1(C(=C)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C)OC(=O)C
- InChIKey
- CKFBRGLGTWAVLG-GOMYTPFNSA-N
- XLogP
- 2.9
- Polar surface area
- 60.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2018
- Admin. routes
- topical
via ChEMBL · EBI
Research
49 papers- Segesterone Acetate.2006
- Nestorone (segesterone acetate) effects on neuroregeneration.Frontiers in neuroendocrinology · 2024
- Segesterone Acetate and Ethinyl Estradiol Vaginal Ring (Annovera) for Contraception.American family physician · 2020
- Segesterone acetate/ethinyl estradiol 12-month contraceptive vaginal system safety evaluation.Contraception · 2019
- Optimized intranasal delivery of segesterone acetate progestin to the brain using nanoemulsions and microemulsions.Drug delivery and translational research · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 370.214
Show 4 more facts
- Commons category
- Segesterone acetate
- chemical formula
- C₂₃H₃₀O₄
- canonical SMILES
- CC(=O)C1(C(=C)CC2C1(CCC3C2CCC4=CC(=O)CCC34)C)OC(=O)C
- isomeric SMILES
- CC(=O)[C@]1(C(=C)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@H]34)C)OC(=O)C
via Wikidata · CC0