Structure via PubChem · Public domain (PubChem)
ulipristal acetate
Sign in to saveAlso known as CDB-2914, VA2914, (11beta,17alpha)-17-acetyl-11-[4-(dimethylamino)phenyl]-3-oxoestra-4,9-dien-17-yl acetate, CDB 2914, 17-acetoxy-11-(4-N,N-dimethylaminophenyl)pregna-4,9-diene-3,20-dione
chemical compound
Chemical data
- Formula
- C30H37NO4
- Molecular weight
- 475.6 g/mol
- IUPAC name
- [(8S,11R,13S,14S,17R)-17-acetyl-11-[4-(dimethylamino)phenyl]-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] acetate
- SMILES
- CC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)OC(=O)C
- InChIKey
- OOLLAFOLCSJHRE-ZHAKMVSLSA-N
- XLogP
- 3.5
- Polar surface area
- 63.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2009
- Admin. routes
- oral
- Indications
- uterine fibroid, Adenomyosis, hemorrhage, leiomyoma
via ChEMBL · EBI
Research
640 papers- Ulipristal Acetate in Adenomyosis.Gynecology and minimally invasive therapy · 2022
- Pre-treatment with GnRHa or ulipristal acetate prior to laparoscopic and laparotomic myomectomy: A systematic review and meta-analysis.PloS one · 2017
- Ulipristal acetate for fibroids.Australian prescriber · 2016
- Ulipristal acetate: in uterine fibroids.Drugs · 2012
- Ulipristal Acetate Before Hysteroscopic Myomectomy: A Systematic Review.Obstetrical & gynecological survey · 2020
via PubMed
Wikidata facts
- Subclass of
- oral contraceptive
- Mass
- 475.272
- Has use
- medication
Show 6 more facts
- chemical formula
- C₃₀H₃₇NO₄
- isomeric SMILES
- CC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)OC(=O)C
- canonical SMILES
- CC(=O)C1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)OC(=O)C
- subject has role
- essential medicine
- Commons category
- Ulipristal acetate
- defined daily dose
- 5
Sources (6)
via Wikidata · CC0