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selumetinib

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Also known as NSC 741O78, ARRY-886, AZD-6244, ARRY-142886, Koselugo, AZD 6244, AZD6244, ARRY142886

Selumetinib (International nonproprietary name|), sold under the brand name Koselugo, is a medication for the treatment of children, two years of age and older, with neurofibromatosis type I (NF-1), a genetic disorder of the nervous system causing tumors to grow on nerves. It is taken by mouth.

~9 min read

Encyclopedic overview

11 sections
Contents
  • Medical uses
  • Adverse effects
  • Pregnancy
  • Interactions
  • Pharmacology
  • Mechanism of action
  • History
  • Research
  • References
  • Further reading
  • External links

Selumetinib (International nonproprietary name|), sold under the brand name Koselugo, is a medication for the treatment of children, two years of age and older, with neurofibromatosis type I (NF-1), a genetic disorder of the nervous system causing tumors to grow on nerves. It is taken by mouth.

Common side effects include headache, abdominal pain and other problems of the gastrointestinal tract, fatigue, muscle pain, as well as dry skin and other skin problems.

Excerpted from Wikipedia’s “selumetinib” article, available under the CC BY-SA 4.0 licence.

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