SH2B1
Sign in to saveAlso known as PSM, SH2B, SH2B adaptor protein 1
SH2B adapter protein 1 is a protein that in humans is encoded by the SH2B1 gene.
In the Vinony graph
Vinony's link graph records 11 inbound references to SH2B1, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under the topic Genes on human chromosome 16.
Vinony links it to 7 Wikipedia language editions.
Gene data
SH2B1- Name
- SH2B adaptor protein 1
- Type
- protein-coding
- Position
- 28,846,584–28,875,103 (+)
- Aliases
- PSM, SH2B
- Ensembl
- ENSG00000178188
- RefSeq RNA
- NM_001145795.2, NM_001145796.2, NM_001145797.2, NM_001145812.2, NM_001308293.2
- RefSeq protein
- NP_001139267.1, NP_001139268.1, NP_001139269.1, NP_001139284.1, NP_001295222.1
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SH2B adaptor protein 1
- Symbol
- SH2B1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:28,846,584-28,875,103
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SH2B1 PDB 2hdv.png
Show 8 more facts
- HomoloGene ID
- 32122
- genetic association
- obesity
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25970
- genomic end
- 28885526
- genomic start
- 28857921
- chromosome
- human chromosome 16
- cytogenetic location
- 16p11.2
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Interactions
- Clinical significance
- See also
- References
- Further reading
SH2B adapter protein 1 is a protein that in humans is encoded by the SH2B1 gene.
== Interactions ==
Excerpted from Wikipedia’s “SH2B1” article, available under the CC BY-SA 4.0 licence.