SLC6A2
Sign in to saveAlso known as NAT1, NET, NET1, SLC6A5, solute carrier family 6 member 2, Norepinephrine transporter, norepinephrine transporter gene
protein-coding gene in the species Homo sapiens
Gene data
SLC6A2- Name
- solute carrier family 6 member 2
- Type
- protein-coding
- Position
- 55,655,961–55,707,645 (+)
- Aliases
- NAT1, NET, NET1, SLC6A5
- Ensembl
- ENSG00000103546
- RefSeq RNA
- NM_001043.3, NM_001172501.3, NM_001172502.1, NM_001172504.1, XM_006721263.2
- RefSeq protein
- NP_001034.1, NP_001165972.1, NP_001165973.1, NP_001165975.1, XP_006721326.1
This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
solute carrier family 6 member 2
- Symbol
- SLC6A2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:55,655,961-55,707,645
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 816
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6530
- genomic end
- 55707645
- genomic start
- 55655988
- chromosome
- human chromosome 16
- cytogenetic location
- 16q12.2
- expressed in
- nipple
via Wikidata · CC0