SOX9
Sign in to saveAlso known as CMD1, CMPD1, SRA1, SRXX2, SRXY10, SRY-box 9, SRY-box transcription factor 9
Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene.
Gene data
SOX9- Name
- SRY-box transcription factor 9
- Type
- protein-coding
- Aliases
- CMD1, CMPD1, ENH13, SRA1, SRXX2, SRXY10, TESCO
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein SOX9 PDB 1S9M.png
Show 5 more facts
- HomoloGene ID
- 294
- exact match
- identifiers.org/ncbigene/6662
- genomic end
- 70122561
- genomic start
- 70117161
- cytogenetic location
- 17q24.3
via Wikidata · CC0
~6 min read
Article
10 sectionsContents
- Function
- Clinical significance
- SOX9 localization and dynamics
- Role in Sexual Differentiation
- Interactions
- Knock out models
- See also
- Further reading
- References
- External links
Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene.
== Function ==
Connections
Sex determining region Y
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Q180686
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Ensembl genome database project
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NR0B1
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KMT2C
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PDX1
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protein
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International Standard Book Number
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Wikidata
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gene
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chromosome
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