SPRED3
Sign in to saveAlso known as Eve-3, spred-3, sprouty related EVH1 domain containing 3
Sprouty-related, EVH1 domain-containing protein 3 also known as Spread-3 is a protein that in humans is encoded by the SPRED3 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to SPRED3, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under topics including EVH1 domain, Genes on human chromosome 19 and SPR domain.
Vinony links it to 5 Wikipedia language editions.
Gene data
SPRED3- Name
- sprouty related EVH1 domain containing 3
- Type
- protein-coding
- Position
- 38,388,421–38,399,588 (+)
- Aliases
- Eve-3, spred-3
- Ensembl
- ENSG00000188766
- RefSeq RNA
- NM_001039616.1, NM_001042522.3, NM_001394336.1, NM_001394337.1, NM_001394338.1
- RefSeq protein
- NP_001035987.1, NP_001381265.1, NP_001381266.1, NP_001381267.1
This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
sprouty related EVH1 domain containing 3
- Symbol
- SPRED3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:38,388,421-38,399,588
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 28061
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/399473
- chromosome
- human chromosome 19
- genomic start
- 38888821
- genomic end
- 38890521
- cytogenetic location
- 19q13.2
- expressed in
- subthalamic nucleus
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Sprouty-related, EVH1 domain-containing protein 3 also known as Spread-3 is a protein that in humans is encoded by the SPRED3 gene.
Spread-3 is a member of the Sprouty (see SPRY1/SPRED) family of proteins that regulate growth factor-induced activation of the MAP kinase cascade.
Excerpted from Wikipedia’s “SPRED3” article, available under the CC BY-SA 4.0 licence.