SPRY4
Sign in to saveAlso known as HH17, sprouty RTK signaling antagonist 4
Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene.
Gene data
SPRY4- Name
- sprouty RTK signaling antagonist 4
- Type
- protein-coding
- Aliases
- HH17
This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8042
- exact match
- identifiers.org/ncbigene/81848
- genomic end
- 141706020
- genomic start
- 141689992
- cytogenetic location
- 5q31.3
Sources (4)
via Wikidata · CC0
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Article
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Protein sprouty homolog 4 is a protein that in humans is encoded by the SPRY4 gene.
== Function ==