ácido meso-2,3-dimercaptosuccínico

Also known as DMSA, Chemet, meso-2,3-dimercaptosuccinic acid, meso-dimercaptosuccinic acid

Succimer, sold under the brand name Chemet among others, is a medication tool used to treat lead, mercury, and arsenic poisoning. When radiolabeled with technetium-99m, it is used in many types of diagnostic testing.

In the Vinony graph

Vinony's link graph records 98 inbound references to ácido meso-2,3-dimercaptosuccínico, and connects out to iron, copper and World Health Organization.

Vinony files it under Chelating agents, Dicarboxylic acids and ECHA InfoCard ID from Wikidata.

Vinony links it to 22 Wikipedia language editions.

Key facts

Drug.legal_US: Rx-only
Drug.H: 6
Drug.O: 4
Drug.CAS_number: 304-55-2
Drug.S: 2
Drug.PubChem: 2724354
Drug.image: Meso-2,3-dimercaptosuccinic-acid-2D-skeletal-A-configurations-labelled.png
Drug.image_class: skin-invert-image
Drug.image2: DMSA-3D-balls.png
Drug.image_class2: bg-transparent
Drug.tradename: Chemet, others
Drug.DailyMedID: Succimer
Drug.ATC_prefix: V03
Drug.ATC_suffix: AB
Drug.DrugBank: DB00566
Drug.ChemSpiderID: 2006502
Drug.UNII: DX1U2629QE
Drug.KEGG: D00572

via Wikipedia infobox

Chemical data

Formula: C4H6O4S2
Molecular weight: 182.2 g/mol
IUPAC name: (2S,3R)-2,3-bis(sulfanyl)butanedioic acid
SMILES: [C@@H]([C@@H](C(=O)O)S)(C(=O)O)S
InChIKey: ACTRVOBWPAIOHC-XIXRPRMCSA-N
XLogP: 0.1
Polar surface area: 76.6 Å²
H-bond donors: 4
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Research

2,622 papers

Succimer, an oral lead chelator.Clinical pharmacy · 1991
Succimer: the first approved oral lead chelator.American family physician · 1993
Succimer chelation in a patient with mercury-associated parkinsonism.Clinical toxicology (Philadelphia, Pa.) · 2024
Arsenic Toxicity: Molecular Targets and Therapeutic Agents.Biomolecules · 2020
Succimer chelation does not produce lasting reductions of blood lead levels in a rodent model of retained lead fragments.Environmental toxicology and pharmacology · 2023

via PubMed

Wikidata facts

Mass: 181.970751
Has use: medication

Show 7 more facts

chemical formula: C₄H₆O₄S₂
isomeric SMILES: OC(=O)[C@@H](S)[C@@H](S)C(O)=O
Commons category: Dimercaptosuccinic acid
medical condition treated: lead poisoning
canonical SMILES: C(C(C(=O)O)S)(C(=O)O)S
NCI Thesaurus ID: C61953
subject has role: essential medicine

Sources (4)

via Wikidata · CC0

Article · Español

El ácido dimercaptosuccínico, conocido también como DMSA o succimer, es un compuesto disulfhidrilo, es decir, con dos grupos sulfhidrilo que es de utilidad en medicina y toxicología en casos de intoxicación por mercurio, arsénico y plomo. Se administra en la forma de para mayor estabilidad.

Abstract from DBpedia / Wikipedia · CC BY-SA