succimer

Key facts

Drug.legal_US

Rx-only

Drug.H

6

Drug.O

4

Drug.CAS_number

304-55-2

Drug.S

2

Drug.PubChem

2724354

Drug.image

Meso-2,3-dimercaptosuccinic-acid-2D-skeletal-A-configurations-labelled.png

Drug.image_class

skin-invert-image

Drug.image2

DMSA-3D-balls.png

Drug.image_class2

bg-transparent

Drug.tradename

Chemet, others

Drug.DailyMedID

Succimer

Drug.ATC_prefix

V03

Drug.ATC_suffix

AB

Drug.DrugBank

DB00566

Drug.ChemSpiderID

2006502

Drug.UNII

DX1U2629QE

Drug.KEGG

D00572

via Wikipedia infobox

Chemical data

Formula

C4H6O4S2

Molecular weight

182.2 g/mol

IUPAC name

(2S,3R)-2,3-bis(sulfanyl)butanedioic acid

SMILES

[C@@H]([C@@H](C(=O)O)S)(C(=O)O)S

InChIKey

ACTRVOBWPAIOHC-XIXRPRMCSA-N

XLogP

0.1

Polar surface area

76.6 Ų

H-bond donors

4

H-bond acceptors

6

Formal charge

0

via PubChem

• Succimer, an oral lead chelator.Clinical pharmacy · 1991
• Succimer: the first approved oral lead chelator.American family physician · 1993
• Succimer chelation in a patient with mercury-associated parkinsonism.Clinical toxicology (Philadelphia, Pa.) · 2024
• Arsenic Toxicity: Molecular Targets and Therapeutic Agents.Biomolecules · 2020
• Succimer chelation does not produce lasting reductions of blood lead levels in a rodent model of retained lead fragments.Environmental toxicology and pharmacology · 2023

via PubMed