Structure via PubChem · Public domain (PubChem)
sulfisomidine
Sign in to saveAlso known as N(1)-(2,6-Dimethyl-4-pyrimidinyl)sulfanilamide, Sulphasomidine, 2,6-Dimethyl-4-sulfanilamidopyrimidine, 6-(p-Aminobenzenesulfonyl)amino-2,4-dimethylpyrimidine, 6-(p-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine, Sulfasomidine, Sulfaisodimidine, 2,4-Dimethyl-6-sulfanilamidopyrimidine
Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003), sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.
Chemical data
- Formula
- C12H14N4O2S
- Molecular weight
- 278.33 g/mol
- IUPAC name
- 4-amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide
- SMILES
- CC1=CC(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)N
- InChIKey
- YZMCKZRAOLZXAZ-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 106 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
180 papers- SULFISOMIDINE.Journal of the American Medical Association · 1957
- Sulfisomidine in the treatment of pertussis.California medicine · 1956
- [Dosage of sulfisomidine].Arzneimittel-Forschung · 1969
- Supramolecular aggregates formed by sulfadiazine and sulfisomidine inclusion complexes with α- and β-cyclodextrins.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2014
- UV-Fenton degradation of diclofenac, sulpiride, sulfamethoxazole and sulfisomidine: Degradation mechanisms, transformation products, toxicity evolution and effect of real water matrix.Chemosphere · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 278.084
Show 3 more facts
- chemical formula
- C₁₂H₁₄N₄O₂S
- canonical SMILES
- CC1=CC(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)N
- Commons category
- Sulfisomidine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Sulfisomidine (INN), also known as sulphasomidine (BAN until 2003), sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.
==References==
Excerpted from Wikipedia’s “sulfisomidine” article, available under the CC BY-SA 4.0 licence.
Available in 10 languages
via Wikidata sitelinks · CC0