THC-O-acetate

THC-O-acetate (THC acetate ester, O-acetyl-THC, THC-O, AcO-THC) is the acetate ester of THC. The term THC-O-acetate is commonly used for two different isomers of this substance, dependent on which isomer of THC it is synthesized from. The difference between Δ8-THC and Δ9-THC is the location of the double bond within the cyclohexene ring system. In naming the esters of THC, the "-O-" is superfluous.

==Physical data, chemistry, and properties== [[Image:D8-THC-O-acetate.svg|class=skin-invert-image|200px|thumb|left|O-acetyl-Δ8-THC CAS# 23050-54-6] class=skin-invert-image|200px|thumb|left|Esters of Δ9-THC: Top (from left); THC acetate, THC propionate, THC phosphate, THC-NE, Bottom; THC morpholinylbutyrate, THC piperidinylpropionate, THC hemisuccinate, THC hemiglutarate THC acetate ester (THC-O or THCOA) can be synthesized from THC, or from THCA. The acetylation of THC does not change the properties of the compound to the same extent as with other acetate esters, as the parent compound (THC) is already highly lipophilic, but potency is nonetheless increased to some extent. While the acetate ester of Δ9-THC is the best studied, the acetate esters of other isomers, especially Δ8-THC but also Δ10-THC are also known, as are other esters such as THC-O-propionate, THC-O-phosphate, THC hemisuccinate, THC hemiglutarate, THC morpholinylbutyrate, THC piperidinylpropionate, THC naphthoyl ester (THC-NE), and THC-VHS, as well as the hydrogenated derivative HHC-O-acetate and the ring-expanded Abeo-HHC acetate, as well as related compounds such as THC methylcarbonate.