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Thiazoline

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Thiazoline

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Thiazolines (; or dihydrothiazoles) are a group of isomeric 5-membered heterocyclic compounds containing both sulfur and nitrogen in the ring. Although unsubstituted thiazolines are rarely encountered themselves, their derivatives are more common and some are bioactive. For example, in a common post-translational modification, cysteine residues are converted into thiazolines.

Chemical data

Formula
C3H5NS
Molecular weight
87.15 g/mol
IUPAC name
4,5-dihydro-1,3-thiazole
SMILES
C1CSC=N1
InChIKey
CBDKQYKMCICBOF-UHFFFAOYSA-N
XLogP
0.4
Polar surface area
37.7 Ų
H-bond donors
0
H-bond acceptors
2
Formal charge
0

via PubChem

Wikidata facts

Mass
87.01427
Show 2 more facts
canonical SMILES
C1CSC=N1
chemical formula
C₃H₅NS
Sources (4)

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Encyclopedic overview

5 sections
Contents
  • Isomers
  • Synthesis
  • Applications
  • See also
  • References

Thiazolines (; or dihydrothiazoles) are a group of isomeric 5-membered heterocyclic compounds containing both sulfur and nitrogen in the ring. Although unsubstituted thiazolines are rarely encountered themselves, their derivatives are more common and some are bioactive. For example, in a common post-translational modification, cysteine residues are converted into thiazolines.

The name thiazoline originates from the Hantzsch–Widman nomenclature.

Excerpted from Wikipedia’s “Thiazoline” article, available under the CC BY-SA 4.0 licence.

Gallery (2)