Thioacetazone (INN, BAN), also known as amithiozone (USAN), is an oral antibiotic which is used in the treatment of tuberculosis. It has fallen into almost complete disuse due to toxicity and the introduction of improved anti-tuberculosis drugs like isoniazid. The drug has only weak activity against Mycobacterium tuberculosis and is only useful in preventing resistance to more powerful drugs such as isoniazid and rifampicin. It is never used on its own to treat tuberculosis; it is used in a similar way to ethambutol.
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 470606762 | IUPAC_name = N-{4-[(Ethanethioamidoimino)methyl]phenyl}acetamide | image = Thioacetazone.svg | image_class = skin-invert-image | alt = Structural formula of thioacetazone | width = 250 | image2 = Thioacetazone 3D spacefill.png | image_class2 = bg-transparent | alt2 = Space-filling model of thioacetazone | width2 = 225
| tradename = Conteben | Drugs.com = | routes_of_administration = Oral
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).