TINF2

Also known as DKCA3, TIN2, TERF1 interacting nuclear factor 2

TERF1-interacting nuclear factor 2 is a protein that in humans is encoded by the TINF2 gene. TINF2 is a component of the shelterin protein complex found at the end of telomeres.

Gene data

TINF2

Name: TERF1 interacting nuclear factor 2
Type: protein-coding
Aliases: DKCA3, DKCA5, TIN2

This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010].

via MyGene.info

Gene · Ensembl

TERF1 interacting nuclear factor 2

Symbol: TINF2
Biotype: Protein coding
Organism: Homo sapiens
Location: 14:24,234,009-24,242,666
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein TINF2 PDB 3BQO.png

Show 5 more facts

HomoloGene ID: 8264
exact match: identifiers.org/ncbigene/26277
genomic end: 24711880
genomic start: 24708849
cytogenetic location: 14q12

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TERF1-interacting nuclear factor 2 is a protein that in humans is encoded by the TINF2 gene. TINF2 is a component of the shelterin protein complex found at the end of telomeres.

== Interactions ==