TLX3
Sign in to saveAlso known as HOX11L2, RNX, T-cell leukemia homeobox 3, T cell leukemia homeobox 3
T-cell leukemia homeobox protein 3 is a protein that in humans is encoded by the TLX3 gene.
Gene data
TLX3- Name
- T cell leukemia homeobox 3
- Type
- protein-coding
- Aliases
- HOX11L2, RNX
The protein encoded by this gene is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults. [provided by RefSeq, Nov 2015].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 23181
- exact match
- identifiers.org/ncbigene/30012
- genomic end
- 171312139
- genomic start
- 171309248
- cytogenetic location
- 5q35.1
Sources (3)
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- References
- Further reading
T-cell leukemia homeobox protein 3 is a protein that in humans is encoded by the TLX3 gene.
RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993).[supplied by OMIM]