transaminase

Also known as aminotransferase, transaminases

Transaminases or aminotransferases are enzymes that catalyze a transamination reaction between an amino acid and an α-keto acid. They are important in the synthesis of amino acids, which form proteins.

Key facts

Protein family.Symbol: Aminotransferase
Protein family.Name: Aminotransferase
Protein family.image: Aspartate transaminase.png
Protein family.caption: Aspartate transaminase from E. coli with Pyridoxal 5' Phosphate cofactor
Protein family.Pfam: PF00155
Protein family.InterPro: IPR004839
Protein family.Membranome superfamily: 273

via Wikipedia infobox

Research

89,359 papers

Tyrosine aminotransferase: a transaminase among others?Cellular and molecular biology · 1992
Transaminases.The Journal of biological chemistry · 1945
Novel D-amino acid transaminase.Annals of the New York Academy of Sciences · 1988
Transaminase and pyridoxine deficiency.The Journal of biological chemistry · 1947
[Transaminase screening test].Orvosi hetilap · 1972

via PubMed

Wikidata facts

Show 1 more fact

EC enzyme number: 2.6.1.-

Sources (3)

via Wikidata · CC0

~4 min read

Article

7 sections

Contents

Function and mechanism
Amino acid metabolism in animals
Diagnostic uses
See also
References
Further reading
External links

Two important transaminase enzymes, aspartate transaminase (AST), and alanine transaminase (ALT), are commonly used as indicators of liver and cardiac health.