Transversion
Sign in to savethumb|right|300px|Illustration of a transversion: each of the 8 nucleotide changes between a purine and a pyrimidine (in red). The 4 other changes are Transition (genetics)|transitions (in blue).
Article
8 sectionsContents
- Ratio of transitions to transversions
- Spontaneous germline transversion
- Consequences of transversion mutations
- Transversions due to products of oxidative guanine damage
- Transversion and p53 mutations in smoking-associated cancers
- See also
- References
- External links
thumb|right|300px|Illustration of a transversion: each of the 8 nucleotide changes between a purine and a pyrimidine (in red). The 4 other changes are Transition (genetics)|transitions (in blue).
Transversion, in molecular biology, refers to a point mutation in DNA in which a single (two ring) purine (A or G) is changed for a (one ring) pyrimidine (T or C), or vice versa. A transversion can be spontaneous, or it can be caused by ionizing radiation or alkylating agents. It can only be reversed by a spontaneous reversion.