TRIO
Sign in to saveAlso known as ARHGEF23, tgat, trio Rho guanine nucleotide exchange factor, MEBAS, MRD44, MRD63, TRIO gene
protein-coding gene in the species Homo sapiens
Gene data
TRIO- Name
- trio Rho guanine nucleotide exchange factor
- Type
- protein-coding
- Position
- 14,143,223–14,532,128 (+)
- Aliases
- ARHGEF23, MEBAS, MRD44, MRD63, tgat
- Ensembl
- ENSG00000038382
- RefSeq RNA
- NM_007118.4, NR_134469.2, XM_011514107.3, XM_011514108.2, XM_011514109.4
- RefSeq protein
- NP_009049.2, XP_011512409.1, XP_011512410.1, XP_011512411.1, XP_011512412.1
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
Gene Ontology
Biological process
cell surface receptor protein tyrosine phosphatase signaling pathwayaxon guidancenegative regulation of fat cell differentiationnegative regulation of fat cell differentiationneuron projection morphogenesisregulation of small GTPase mediated signal transductionpostsynaptic modulation of chemical synaptic transmissionpostsynaptic modulation of chemical synaptic transmission
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
trio Rho guanine nucleotide exchange factor
- Symbol
- TRIO
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:14,143,223-14,532,128
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein TRIO PDB 1nty.png
Show 7 more facts
- HomoloGene ID
- 20847
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7204
- genomic end
- 14532235
- genomic start
- 14143342
- chromosome
- human chromosome 5
- cytogenetic location
- 5p15.2
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