TTPA
Sign in to saveAlso known as ATTP, AVED, TTP1, alphaTTP, tocopherol (alpha) transfer protein, alpha tocopherol transfer protein
protein-coding gene in the species Homo sapiens
Gene data
TTPA- Name
- alpha tocopherol transfer protein
- Type
- protein-coding
- Position
- 63,048,139–63,086,197 (−)
- Aliases
- ATTP, AVED, TTP1, alphaTTP
- Ensembl
- ENSG00000137561
- RefSeq RNA
- NM_000370.3, NM_001413414.1, NM_001413415.1, NM_001413416.1, NM_001413417.1
- RefSeq protein
- NP_000361.1, NP_001400343.1, NP_001400344.1, NP_001400345.1, NP_001400346.1
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa. [provided by RefSeq, Nov 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
alpha tocopherol transfer protein
- Symbol
- TTPA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:63,048,139-63,086,197
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- 5mug.jpg
Show 7 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 37295
- exact match
- identifiers.org/ncbigene/7274
- genomic end
- 63998612
- genomic start
- 63961112
- chromosome
- human chromosome 8
- cytogenetic location
- 8q12.3
via Wikidata · CC0