MOCS1
Sign in to saveAlso known as MIG11, MOCOD, MOCODA, molybdenum cofactor synthesis 1, MOCS1A, MOCS1B
Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene.
Gene data
MOCS1- Name
- molybdenum cofactor synthesis 1
- Type
- protein-coding
- Position
- 39,899,578–39,934,551 (−)
- Aliases
- MIG11, MOCOD, MOCS1A, MOCS1B
- Ensembl
- ENSG00000124615
- RefSeq RNA
- NM_001075098.4, NM_001358529.2, NM_001358530.2, NM_001358531.2, NM_001358533.2
- RefSeq protein
- NP_001068566.1, NP_001345458.1, NP_001345459.1, NP_001345460.1, NP_001345462.1
Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq, Nov 2017].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
molybdenum cofactor synthesis 1
- Symbol
- MOCS1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:39,899,578-39,934,551
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene.
Both copies of this gene are defective in patients with molybdenum cofactor deficiency, type A.
Excerpted from Wikipedia’s “MOCS1” article, available under the CC BY-SA 4.0 licence.