TXLNA
Sign in to saveAlso known as IL14, TXLN, IL-14, taxilin alpha
Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA gene.
Gene data
TXLNA- Name
- taxilin alpha
- Type
- protein-coding
- Position
- 32,178,097–32,198,299 (+)
- Aliases
- IL-14, IL14, TXLN
- Ensembl
- ENSG00000084652
- RefSeq RNA
- NM_001376857.1, NM_001376858.1, NM_001376859.1, NM_175852.4, XM_011540932.3
- RefSeq protein
- NP_001363786.1, NP_001363787.1, NP_001363788.1, NP_787048.1, XP_011539234.1
Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis. Predicted to act upstream of or within B cell activation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
taxilin alpha
- Symbol
- TXLNA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:32,178,097-32,198,299
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Gene
- References
- External links
- Further reading
Alpha-taxilin also known as interleukin-14 (IL-14) or high molecular weight B-cell growth factor (HMW-BCGF) is a protein that in humans is encoded by the TXLNA gene.
Interleukin-14 is a cytokine that controls the growth and proliferation of both normal and cancerous B cells. This molecule was also recently designated taxilin. IL-14 induces B-cell proliferation, inhibits antibody secretion, and expands selected B-cell subgroups. This interleukin is produced mainly by T cells and certain malignant B cells.
Excerpted from Wikipedia’s “TXLNA” article, available under the CC BY-SA 4.0 licence.