Structure via PubChem · Public domain (PubChem)
tybamate
Sign in to saveAlso known as Effisax
Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker.
Chemical data
- Formula
- C13H26N2O4
- Molecular weight
- 274.36 g/mol
- IUPAC name
- [2-(carbamoyloxymethyl)-2-methylpentyl] N-butylcarbamate
- SMILES
- CCCCNC(=O)OCC(C)(CCC)COC(=O)N
- InChIKey
- PRBORDFJHHAISJ-UHFFFAOYSA-N
- XLogP
- 2.4
- Polar surface area
- 90.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 274.189
Show 3 more facts
- chemical formula
- C₁₃H₂₆N₂O₄
- canonical SMILES
- CCCCNC(=O)OCC(C)(CCC)COC(=O)N
- Commons category
- Tybamate
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Tybamate (INN; Solacen, Tybatran, Effisax) is an anxiolytic of the carbamate family. It is a prodrug for meprobamate in the same way as the better known drug carisoprodol. It has liver enzyme inducing effects similar to those of phenobarbital but much weaker.
As the trade name Tybatran (Robins), it was formerly available in capsules of 125, 250, and 350 mg, taken 3 or 4 times a day for a total daily dosage of 750 mg to 2 g. The plasma half-life of the drug is three hours. At high doses in combination with phenothiazines, it could produce convulsions.
Excerpted from Wikipedia’s “tybamate” article, available under the CC BY-SA 4.0 licence.
Gallery (2)
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