TYMP
Sign in to saveAlso known as thymidine phosphorylase, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP
Gen der Spezies Homo sapiens
Gene data
TYMP- Name
- thymidine phosphorylase
- Type
- protein-coding
- Position
- 50,525,752–50,530,326 (−)
- Aliases
- ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
- Ensembl
- ENSG00000025708
- RefSeq RNA
- NM_001113755.3, NM_001113756.3, NM_001257988.1, NM_001257989.1, NM_001953.5
- RefSeq protein
- NP_001107227.1, NP_001107228.1, NP_001244917.1, NP_001244918.1, NP_001944.1
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012].
Gene Ontology
Biological process
pyrimidine nucleobase metabolic processpyrimidine nucleoside metabolic processpyrimidine nucleoside metabolic processpyrimidine nucleoside metabolic processdTMP catabolic processnucleobase-containing small molecule metabolic processpyrimidine-containing compound metabolic processcarbohydrate derivative metabolic process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
thymidine phosphorylase
- Symbol
- TYMP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:50,525,752-50,530,326
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ECGF1 PDB 1uou.png
Show 8 more facts
- HomoloGene ID
- 1474
- exact match
- identifiers.org/ncbigene/1890
- found in taxon
- Homo sapiens
- genomic end
- 50530032
- genomic start
- 50964181
- chromosome
- human chromosome 22
- Commons category
- Thymidine phosphorylase
- cytogenetic location
- 22q13.33
via Wikidata · CC0