diabetic nephropathy
Sign in to saveAlso known as diabetic kidney disease, Nephropatia diabetica, diabetes mellitus insulin dependent type not stated as uncontrolled with renal manifestations, Diabetes mellitus juvenile type, not stated as uncontrolled, with renal manifestations, Diabetes mellitus type I [insulin dependent type] [IDDM] [juvenile type], not stated as uncontrolled, with renal manifestations, diabetes mellitus insulin dependent type uncontrolled with renal manifestations, Diabetes mellitus juvenile type, uncontrolled, with renal manifestations, Diabetes mellitus type I [juvenile type], uncontrolled, with renal manifestations
disease
In the Vinony graph
Within Vinony's link graph, diabetic nephropathy is referenced by 219 other articles, and connects out to chronic renal insufficiency, diabetes and blood glucose.
Vinony files it under Complications of diabetes, Kidney diseases and Vascular diseases.
Its subject is documented across 34 Wikipedia language editions.
Key facts
- Other names
- Diabetic kidney disease
- Specialty
- Nephrology , endocrinology
- Symptoms
- Albuminuria , peripheral edema , high blood pressure, tiredness
- Risk factors
- High blood pressure, tobacco smoking , unstable blood glucose
- Diagnostic method
- Abnormal levels of urinary albumin
- Prevention
- Smoking cessation
- Treatment
- ACE inhibitors
via Wikipedia infobox
Health references
- ICD-10
- E10.21 — Type 1 diabetes mellitus with diabetic nephropathy
- MedlinePlus
- Consumer health page →
Research
48,019 papers- Diabetic Nephropathy: Pathogenesis, Mechanisms, and Therapeutic Strategies.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2025
- Diabetic nephropathy.Diabetes care · 2005
- Epigenetics in the pathogenesis of diabetic nephropathy.Acta biochimica et biophysica Sinica · 2022
- Classification and Differential Diagnosis of Diabetic Nephropathy.Journal of diabetes research · 2017
- Diabetic nephropathy.Clinical cornerstone · 2003
via PubMed
Clinical Trials
722 registered- COMPLETEDSodium Glucose Co-Transporter 2 Inhibitors on Estimated Glomerular Filtration Rate in Diabetic Versus Non-Diabetic Chronic Kidney Disease PatientsAin Shams University · NCT07302464
- PHASE2WITHDRAWNP2a Open Label Study to Evaluate 2-HPβCD in Subjects With Diabetic Kidney DiseaseZyVersa Therapeutics, Inc. · NCT06489340
- NOT_YET_RECRUITINGAssessment of Serum Magnesium Level with Diabetic Foot Ulceration in Type II Diabetes Associated with Diabetic Nephropathy PatientsAssiut University · NCT06754878
- NACOMPLETEDEffects of Febuxostat on Adipokines and Kidney Disease in Diabetic Chronic Kidney DiseaseUniversity of Utah · NCT01350388
- COMPLETEDSerum 1,25-dihydroxyvitamin D Levels in Type 2 Diabetes Mellitus Patients With Different Levels of AlbuminuriaTianjin Medical University General Hospital · NCT01845870
- PHASE2COMPLETEDA Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt NephropathyPfizer · NCT01200394
Wikidata facts
- Instance of
- disease
- Subclass of
- complications of diabetes mellitus
- Image
- Nodular glomerulosclerosis.jpeg
Show 8 more facts
- NCI Thesaurus ID
- C84417
- health specialty
- endocrinology
- Commons category
- Diabetic nephropathy
- ICD-9-CM
- 250.4
- drug or therapy used for treatment
- pregabalin
- exact match
- identifiers.org/doid/DOID:2370
- on focus list of Wikimedia project
- WikiProject Medicine
Sources (7)
via Wikidata · CC0
~16 min read
Encyclopedic overview
Diabetic nephropathy (DN), also known as diabetic kidney disease (DKD), is a chronic loss of kidney function in those with diabetes mellitus (diabetes), affecting approximately one quarter of adults in the United States. DN is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) worldwide. The condition is commonly associated with proteinuria (protein in the urine), hypertension, and declining renal function over time.
Affected individuals with ESKD often require hemodialysis and eventually kidney transplantation to replace the failed kidney function. DN is associated with an increased risk of death in general, particularly from cardiovascular disease.
Excerpted from Wikipedia’s “diabetic nephropathy” article, available under the CC BY-SA 4.0 licence.