Structure via PubChem · Public domain (PubChem)
U-47700
Sign in to saveAlso known as U4, pinky
U-47700, also known as U4, pink heroin, pinky, and pink, is an opioid analgesic drug developed by a team at Upjohn in the 1970s which has around 7.5 times the potency of morphine in animal models. thumb|Physical Sample of U-47700 U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the
Chemical data
- Formula
- C16H22Cl2N2O
- Molecular weight
- 329.3 g/mol
- IUPAC name
- 3,4-dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide
- SMILES
- CN(C)[C@@H]1CCCC[C@H]1N(C)C(=O)C2=CC(=C(C=C2)Cl)Cl
- InChIKey
- JGPNMZWFVRQNGU-HUUCEWRRSA-N
- XLogP
- 4
- Polar surface area
- 23.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 328.110918684
- Image
- Sample of U-47700.png
Show 4 more facts
- isomeric SMILES
- CN(C)[C@@H]1CCCC[C@H]1N(C)C(=O)C2=CC(=C(C=C2)Cl)Cl
- chemical formula
- C₁₆H₂₂Cl₂N₂O
- canonical SMILES
- CN(C)C1CCCCC1N(C)C(=O)C2=CC(=C(C=C2)Cl)Cl
- Commons category
- U-47700
Sources (1)
via Wikidata · CC0
~4 min read
Encyclopedic overview
9 sectionsContents
- Pharmacology
- Side effects
- Deaths
- Detection in biological fluids
- Society and culture
- Legal status
- In popular culture
- See also
- References
U-47700, also known as U4, pink heroin, pinky, and pink, is an opioid analgesic drug developed by a team at Upjohn in the 1970s which has around 7.5 times the potency of morphine in animal models. thumb|Physical Sample of U-47700 U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a pyrrolidine rather than a dimethylamine substituent) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
Excerpted from Wikipedia’s “U-47700” article, available under the CC BY-SA 4.0 licence.