ULK1
Sign in to saveAlso known as ATG1, ATG1A, UNC51, Unc51.1, hATG1, unc-51 like autophagy activating kinase 1
Serine/threonine-protein kinase ULK1 is an enzyme that in humans is encoded by the ULK1 gene.
Gene data
ULK1- Name
- unc-51 like autophagy activating kinase 1
- Type
- protein-coding
- Position
- 131,894,596–131,923,161 (+)
- Aliases
- ATG1, ATG1A, UNC51, Unc51.1, hATG1
- Ensembl
- ENSG00000177169
- RefSeq RNA
- NM_003565.4, XM_011538798.4, XM_011538799.3, XM_054373404.1, XM_054373405.1
- RefSeq protein
- NP_003556.2, XP_011537100.1, XP_011537101.1, XP_054229379.1, XP_054229380.1
Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; positive regulation by symbiont of host autophagy; and protein phosphorylation. Located in autophagosome; cytosol; and phagophore assembly site membrane. Is extrinsic component of autophagosome membrane; extrinsic component of omegasome membrane; and extrinsic component of phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
unc-51 like autophagy activating kinase 1
- Symbol
- ULK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:131,894,596-131,923,161
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2640
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8408
- genomic end
- 131923150
- genomic start
- 131894622
- chromosome
- human chromosome 12
- cytogenetic location
- 12q24.33
- expressed in
- nucleus accumbens
via Wikidata · CC0