VAMP2

Name

vesicle associated membrane protein 2

Type

protein-coding

Position

8,159,149–8,163,584 (−)

Aliases

NEDHAHM, SYB2, VAMP-2

Ensembl

ENSG00000220205

RefSeq RNA

NM_001330125.1, NM_014232.3

RefSeq protein

NP_001317054.1, NP_055047.2

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

vesicle associated membrane protein 2

Symbol

VAMP2

Biotype

Protein coding

Organism

Homo sapiens

Location

17:8,159,149-8,163,584

Strand

Reverse (−)

Assembly

GRCh38